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The Risk of recurrence in prostate cancerby: Fritz Frei Prostate cancer disease Prostate cancer - the most common form of cancer in men is Prostate cancer, the second leading cause of cancer death. The Main risk factors include age (incidence increases in men over the age of 65 years). It is more prevalent in the western world and about 10% of cases can be linked to family history. The recurrance Rate of the prostate cancer is high. Mostly, the Prostate cancer is a continuum; progressing through localized, locally advanced, advanced and hormone-refractory stages In general it is a slow growing cancer. He is primarily under hormonal control i.e. testosterone. The choice of treatments which include watchful waiting, surgery (prostatectomy), radiotherapy, hormonal therapy and chemotherapy are dependent on the stage of disease. 1. Most important, that If detected early, using PSA determination, DRE examination and biopsies, and treated appropriately, survival rates are excellent. 2. The most critical focus for the treatment of prostate cancer is to treat those cancers where it is necessary. 3. The Decisions about the best management of prostate cancer can be very complex and depend upon the: - Pathology of the cancer (unlike other cancers, prostate cancer often progresses very slowly) - The impact that treatment can have on quality of life, including sexual activity - Stage of the disease (non-metastatic (localized or locally advanced), metastatic or hormone refractory) - Age and general health of the patients at diagnosis - Patient’s preference for treatment - PSA at diagnosis 4. The treatment options for prostate cancer are: - Deferred treatment often called ‘watchful waiting’ or 'active surveillance' - Surgery – Radical Prostatectomy - Radiotherapy – External Beam and/or Brachytherapy -Hormonal (endocrine) therapy – Androgen Ablation e.g. anti-androgens, medical castration (LHRHa) or surgical castration - Chemotherapy - Palliative Therapy e.g. chemotherapy - Investigational Therapies Prostate Cancer Recurrence Rates *** Prostate cancer is now detected at earlier stages due to heightened awareness and improved screening techniques. Despite definitive therapy, cancer cells may remain and can go undetected for years until they develop into metastatic disease. The risk of recurrence is high, suggesting there is a need to improve treatment approaches. Therefore, it is important to predict pathological stage and risk of disease recurrence early, so that appropriate treatment and/or monitoring can be initiated. The result's of all new treatments will bring us in the future the chance of a lower prostate recurrance. **You can inform you about the recurrence Rates on: http://www.prostateline.com/prostatelinehcp/9898_15850_8_0_0.aspx This gives you an overview with a study case – and the results. Health-Service-Online Admin Fritz http://www.cancer-info.info Latest Cancer News:Hormone drugs for prostate cancer may hurt heart (Reuters via Yahoo! News) Prostate cancer treatments that cut off the supply of male hormone raise cholesterol, worsen blood sugar and make men fatter and thus likely raise the risk of heart attack, too, doctors said on Monday. Auriemma to donate ties on eBay for cancer fund (AP via Yahoo! Sports) Geno Auriemma plans to auction off the neck ties he wears during the rest of UConn's games this season. The school says money raised by the auctions will benefit the Kay Yow/WBCA Cancer Fund. The North Carolina State University women's basketball coach died a year ago after a long fight with breast cancer. Approval Expanded for Breast Cancer Drug Tykerb (HealthDay via Yahoo! News) MONDAY, Feb. 1 (HealthDay News) -- The U.S. Food and Drug Administration has expanded approval for Tyberb (lapatinib) to include postmenopausal women with hormone- and HER2-positive advanced breast cancer who require hormone therapy. Cancer, Autism Push By Obama to Spur New Medicines (Update2) (Bloomberg) Feb. 1 (Bloomberg) -- President Barack Obama proposed increasing the National Institutes of Health budget by $1 billion, or 3.2 percent, in fiscal 2011, earmarking $6 billion for cancer research and $222 million for work in autism. Heart Risk From Prostate Cancer Hormone Therapy (WebMD) Androgen-blocking hormone therapy for prostate cancer may raise the risk of heart disease, warns an expert panel representing heart, cancer, and urology organizations. Cancer, Autism Push in Obama Budget Plan to Spur 30 New Drugs (Bloomberg) Feb. 1 (Bloomberg) -- President Barack Obama increased the National Institutes of Health budget proposal by $1 billion, or 3.2 percent, in fiscal 2011, earmarking $6 billion for cancer research and $222 million for work in autism. Targeting Cancer Stem Cells May Eradicate Tumors (MedicineNet.com) Title: Targeting Cancer Stem Cells May Eradicate Tumors Category: Health News Created: 1/29/2010 4:10:00 PM Last Editorial Review: 2/1/2010 Three-Fourths of Cancer Patients Have Severe Flares of Pain (MedicineNet.com) Title: Three-Fourths of Cancer Patients Have Severe Flares of Pain Category: Health News Created: 1/29/2010 12:10:00 PM Last Editorial Review: 2/1/2010 Scammer Allegedly Lies About Cancer (ABC News) Prosecutor says Md. woman lied about terminal cancer to steal money. Cancer - Health - Conditions and Diseases - Organizations - United States Childhood cancer project under way (Chicago Sun-Times) What's touted as the biggest effort ever to find all of the genetic mutations that cause childhood cancer is now under way. The privately funded project will complement the Cancer Genome Atlas,an eight-year National Institutes of Health initiative focusing largelyon adult malignancies, says NIH director Dr. Francis Collins. Genetic screening for breast cancer risk offer small benefit--study - The Money Times
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